Linked Life Data

9592930

Source:http://linkedlifedata.com/resource/pubmed/id/9592930

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1998-6-19
pubmed:abstractText
In addition to in vivo and in vitro methods, models of structural and theoretical biochemistry as well as bioorganic studies were found to be useful for understanding metabolic activity on a molecular basis. Metabolism of an AChE inhibitor, carbofuran was studied. Product selectivity observed in vitro and in vivo was explained by theoretical methods. Metabolic profiles can be reproduced using P450 mimic synthetic porphyrins. Insight into the mechanism of metabolic reactions might be applied for the identification of metabolically sensitive substructures as well as for the prediction of metabolic profiles.
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0001-6659
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
65-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[Application of theoretical and synthetic models to cytochrome P450 catalysed metabolic reactions].
pubmed:affiliation
CHINOIN Növényoédószer Uzletág, Kémiai Kutatólaboratórium I., Budapest.
pubmed:publicationType
Journal Article, English Abstract