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9587957
Source:
http://linkedlifedata.com/resource/pubmed/id/9587957
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62
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0026549
,
umls-concept:C0031327
,
umls-concept:C0034693
,
umls-concept:C0034721
,
umls-concept:C0242643
,
umls-concept:C0527835
,
umls-concept:C0851347
,
umls-concept:C1280500
,
umls-concept:C1999216
pubmed:issue
4
pubmed:dateCreated
1998-7-23
pubmed:abstractText
The objective of this study was to evaluate the effect of a potent P-gp inhibitor, GF120918, on the systemic pharmacokinetics and antinociceptive pharmacodynamics of a single intravenous dose of morphine in rats.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/GM41935
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/8406521
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Acridines
,
http://linkedlifedata.com/resource/pubmed/chemical/Analgesics, Opioid
,
http://linkedlifedata.com/resource/pubmed/chemical/GF 120918
,
http://linkedlifedata.com/resource/pubmed/chemical/Isoquinolines
,
http://linkedlifedata.com/resource/pubmed/chemical/Morphine
,
http://linkedlifedata.com/resource/pubmed/chemical/Morphine Derivatives
,
http://linkedlifedata.com/resource/pubmed/chemical/P-Glycoprotein
,
http://linkedlifedata.com/resource/pubmed/chemical/Tetrahydroisoquinolines
,
http://linkedlifedata.com/resource/pubmed/chemical/morphine-3-glucuronide
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0724-8741
pubmed:author
pubmed-author:BrouwerK LKL
,
pubmed-author:BrouwerK RKR
,
pubmed-author:LetrentS PSP
,
pubmed-author:PollackG MGM
pubmed:issnType
Print
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
599-605
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:9587957-Acridines
,
pubmed-meshheading:9587957-Administration, Oral
,
pubmed-meshheading:9587957-Analgesia
,
pubmed-meshheading:9587957-Analgesics, Opioid
,
pubmed-meshheading:9587957-Animals
,
pubmed-meshheading:9587957-Area Under Curve
,
pubmed-meshheading:9587957-Dose-Response Relationship, Drug
,
pubmed-meshheading:9587957-Injections, Intravenous
,
pubmed-meshheading:9587957-Isoquinolines
,
pubmed-meshheading:9587957-Male
,
pubmed-meshheading:9587957-Morphine
,
pubmed-meshheading:9587957-Morphine Derivatives
,
pubmed-meshheading:9587957-P-Glycoprotein
,
pubmed-meshheading:9587957-Rats
,
pubmed-meshheading:9587957-Rats, Sprague-Dawley
,
pubmed-meshheading:9587957-Tetrahydroisoquinolines
pubmed:year
1998
pubmed:articleTitle
Effect of GF120918, a potent P-glycoprotein inhibitor, on morphine pharmacokinetics and pharmacodynamics in the rat.
pubmed:affiliation
School of Pharmacy, Division of Pharmaceutics, University of North Carolina at Chapel Hill 27599, USA.
pubmed:publicationType
Journal Article
,
Comparative Study
,
Research Support, U.S. Gov't, P.H.S.
,
Research Support, Non-U.S. Gov't