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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1998-5-21
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pubmed:abstractText |
We report a case of granulomatous mycosis fungoides that progressed into fatal gastrointestinal involvement 4 years after the onset of skin lesions, despite improvement of the skin lesions in response to a combination of PUVA and systemic interferon-gamma therapy. Histological examination showed Pautrier's microabscesses with granuloma annulare-like features and sarcoidal granuloma formation in the plaque stage, proliferation of blast-transformed atypical lymphocytes with persistent granuloma formation in the tumour stage, and metastatic lesions. A literature review of granulomatous mycosis fungoides revealed that 11 of the 24 reported cases died of the disease, and like our case, seven died within 5 years. We suggest that mycosis fungoides with granulomatous reactions does not indicate a favourable prognosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
138
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
522-5
|
pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:9580813-Aged,
pubmed-meshheading:9580813-Fatal Outcome,
pubmed-meshheading:9580813-Granuloma,
pubmed-meshheading:9580813-Humans,
pubmed-meshheading:9580813-Intestine, Small,
pubmed-meshheading:9580813-Male,
pubmed-meshheading:9580813-Mycosis Fungoides,
pubmed-meshheading:9580813-Neoplasm Invasiveness,
pubmed-meshheading:9580813-Skin Neoplasms
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pubmed:year |
1998
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pubmed:articleTitle |
Granulomatous mycosis fungoides with small intestinal involvement and a fatal outcome.
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pubmed:affiliation |
Division of Dermatology, Ogikubo Hospital, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Review,
Case Reports
|