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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-6-8
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pubmed:abstractText |
Screening for congenital hypothyroidism was carried out by measuring thyroid stimulating hormone (TSH) on dried blood spots (mean + 2SD cut off value 12 microU/ml) by fluoroimmunoassay using DELFIA kits. A total of 20,021 infants were screened, and seven cases with congenital hypothyroidism were detected, giving an incidence of congenital hypothyroidism of 1:2860 (female:male ratio 6:1). In four of seven infants with congenital hypothyroidism (57%) the mother also had thyroid disease, supporting the importance of genetic factors as a cause of congenital hypothyroidism. Transient hyperthyrotropinaemia occurred in 654 infants (recall rate 3.3%). There was a significant association of transient hyperthyrotropinaemia only with cardiac failure at birth or caesarean section (p < 0.01). Family studies showed no predisposition to thyroid diseases associated with a transient increase of TSH.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0969-1413
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
20-1
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9575454-Congenital Hypothyroidism,
pubmed-meshheading:9575454-Estonia,
pubmed-meshheading:9575454-Female,
pubmed-meshheading:9575454-Humans,
pubmed-meshheading:9575454-Hypothyroidism,
pubmed-meshheading:9575454-Infant, Newborn,
pubmed-meshheading:9575454-Male,
pubmed-meshheading:9575454-Neonatal Screening,
pubmed-meshheading:9575454-Thyroid Hormones
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pubmed:year |
1998
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pubmed:articleTitle |
Neonatal screening for congenital hypothyroidism in Estonia.
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pubmed:affiliation |
Department of Human Biology and Genetics, University of Tartu, Estonia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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