Linked Life Data

9574703

Source:http://linkedlifedata.com/resource/pubmed/id/9574703

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1998-6-9
pubmed:abstractText
Long-term colonization of various body sites with a multidrug-resistant Pseudomonas aeruginosa clone (resistant to piperacillin, cefoperazone, ceftazidime, aztreonam, imipenem, cefepime, cefpirome, ofloxacin, ciprofloxacin, minocycline, and aminoglycosides) with subsequent severe infections in burn patients has not been reported previously. Thirty-nine isolates of multidrug-resistant P. aeruginosa (resistant to ceftazidime and at least three of the agents listed above) recovered from various clinical samples from three patients in an intensive care burn unit from April 1997 to May 1997 and seven preserved isolates recovered from six patients in other medical wards at National Taiwan University Hospital from April 1996 to May 1997 were studied for their epidemiological relatedness. The epidemic could be attributed to a multidrug-resistant P. aeruginosa clone belonging to serogroup O:F (serogroup O:4) by means of antimicrobial susceptibility testing, O serogrouping, and analysis of the randomly amplified polymorphic DNA patterns generated by arbitrarily primed PCR of the isolates. The epidemic strain persisted in the three patients for weeks to months; in the meantime, these patients had received multiple antimicrobial agents for the management of intervening episodes of invasive infections (bacteremia, ventilator-associated pneumonia, and/or catheter-related sepsis) caused by this strain, as well as concomitant infections due to other organisms. The strain had been isolated only once previously, from a burn patient who was on the unit in December 1996. The present report, describing a small outbreak due to P. aeruginosa, documents the fact that a single clone of multidrug-resistant P. aeruginosa can cause long-term persistence in different body sites of burn patients and that the colonization can subsequently result in various severe infections.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-1457665, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-2514112, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-3086274, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-3104483, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-3924612, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-6815529, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-6820399, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-7544364, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-7559985, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-7751352, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-7913482, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-8104208, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-8258014, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-8748305, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-8818879, http://linkedlifedata.com/resource/pubmed/commentcorrection/9574703-9211157
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0095-1137
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1347-51
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Persistence of a multidrug-resistant Pseudomonas aeruginosa clone in an intensive care burn unit.
pubmed:affiliation
Department of Laboratory Medicine, National Taiwan University Hospital, Taipei.
pubmed:publicationType
Journal Article