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pubmed:abstractText |
We tested the hypothesis that schizophrenia is primarily a frontostriatal disorder by examining executive function in first-episode patients. Previous studies have shown either equal decrements in many cognitive domains or specific deficits in memory. Such studies have grouped test results or have used few executive measures, thus, possibly losing information. We, therefore, measured a range of executive ability with tests known to be sensitive to frontal lobe function.
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pubmed:affiliation |
Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Charing Cross Hospital, Queen Mary's University Hospital, London.
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