Linked Life Data

957167

Source:http://linkedlifedata.com/resource/pubmed/id/957167

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-10-20
pubmed:abstractText
1. Using single fibre vagal afferent recording, we have studied the behavior of slowly adapting stretch receptors located in an isolated, in situ, segment of the trachea in dogs. Responses to positive and negative steady and oscillating transmural pressures were investigated. 2. Seventy-eight per cent of the receptors studied were tonically active at resting tracheal volume. Ninety per cent showed a more pronounced response to positive than to negative transmural pressures. 3. During pressure oscillations the majority of the receptors had a higher discharge frequency at any given pressure during the ascending phase of the pressure wave than at the same pressure under static conditions. During most of the ensuing descent of pressure toward zero the discharge frequency led transmural pressure. 4. With increasing frequency of oscillation the differences from the static responses increased (dP/dt sensitivity), especially during the ascending limb of the pressure oscillation (rectifying behavior). 5. In a small number of receptors, discharge frequency lagged behind transmural pressure or was in phase with it ("no loop" pattern). 6. In three cases the same receptor exhibited dP/dt sensitivity during positive pressure oscillations, whereas discharge frequency lagged behind pressure during negative pressure oscillations. This indicates that the lack of dP/dt sensitivity exhibited under negative pressure conditions does not represent an intrinsic property of these receptors, but reflects some aspect of their mechanical arrangement within the airway wall. 7. THESE PATTERNS OF RESPONSE ARE DISCUSSed in terms of intrinsic and extrinsic characteristics of the receptors. 8. The physiological implications of stretch receptor behaviour are also considered.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-1249602, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-13131247, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-13402923, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-13881160, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-14155280, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-16994466, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-4269825, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-4730755, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-4846941, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-5033464, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-5178800, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-5575377, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-5796467, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-5796468, http://linkedlifedata.com/resource/pubmed/commentcorrection/957167-957165
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0022-3751
pubmed:author
pubmed:issnType
Print
pubmed:volume
258
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
421-32
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Transduction properties of tracheal stretch receptors.
pubmed:publicationType
Journal Article