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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-6-2
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pubmed:databankReference | |
pubmed:abstractText |
The nucleotide sequence of a 700 basepair cDNA obtained from rabbit bladder was determined. It encodes a 123 amino acid protein, which is the smallest member of histone H2A.F/Z subfamily. The known H2A.F/Z variants are highly conserved in their central core regions of about 100 amino acids but more divergent in their N- and C-terminal ends. In addition to the seven amino acid signature sequence previously known for the H2A proteins, all the cloned H2A.F/Z variants contain an identical peptide sequence, L-E-Y-L-T-A-E-V-L-E-L-A-G-N-A. This 15 amino acid motif is proposed here as the signature sequence to identify new members of the H2A.F/Z subfamily.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0006-291X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
245
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
613-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9571203-Amino Acid Sequence,
pubmed-meshheading:9571203-Animals,
pubmed-meshheading:9571203-Base Sequence,
pubmed-meshheading:9571203-Cloning, Molecular,
pubmed-meshheading:9571203-Conserved Sequence,
pubmed-meshheading:9571203-Databases, Factual,
pubmed-meshheading:9571203-Histones,
pubmed-meshheading:9571203-Molecular Sequence Data,
pubmed-meshheading:9571203-Phylogeny,
pubmed-meshheading:9571203-RNA, Messenger,
pubmed-meshheading:9571203-Rabbits,
pubmed-meshheading:9571203-Sequence Alignment,
pubmed-meshheading:9571203-Sequence Analysis, DNA,
pubmed-meshheading:9571203-Sequence Homology, Amino Acid,
pubmed-meshheading:9571203-Urinary Bladder
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pubmed:year |
1998
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pubmed:articleTitle |
Histone H2A.F/Z subfamily: the smallest member and the signature sequence.
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pubmed:affiliation |
Department of Biochemistry and Molecular Biology, Pennsylvania State University College of Medicine, Hershey 17033, USA. wjiang@psu.edu
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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