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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1998-6-18
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pubmed:databankReference |
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pubmed:abstractText |
Autoantibodies with specificity for the E2 component of the pyruvate dehydrogenase complex (PDC-E2) are commonly present in primary biliary cirrhosis. The aim of this study was to generate and characterise human anti-PDC-E2 monoclonal antibodies and analyse immunoglobulin gene usage and mutation for clues to pathogenesis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
582-94
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pubmed:dateRevised |
2009-9-29
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pubmed:meshHeading |
pubmed-meshheading:9566826-Amino Acid Sequence,
pubmed-meshheading:9566826-Antibodies, Monoclonal,
pubmed-meshheading:9566826-Antibody Specificity,
pubmed-meshheading:9566826-Antigen-Antibody Reactions,
pubmed-meshheading:9566826-Dihydrolipoyllysine-Residue Acetyltransferase,
pubmed-meshheading:9566826-Female,
pubmed-meshheading:9566826-Genetic Code,
pubmed-meshheading:9566826-Humans,
pubmed-meshheading:9566826-Immunoblotting,
pubmed-meshheading:9566826-Immunogenetics,
pubmed-meshheading:9566826-Immunoglobulin G,
pubmed-meshheading:9566826-Immunoglobulin M,
pubmed-meshheading:9566826-Liver Cirrhosis, Biliary,
pubmed-meshheading:9566826-Molecular Sequence Data,
pubmed-meshheading:9566826-Mutation,
pubmed-meshheading:9566826-Pyruvate Dehydrogenase Complex
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pubmed:year |
1998
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pubmed:articleTitle |
Immunogenetic analysis of a panel of monoclonal IgG and IgM anti-PDC-E2/X antibodies derived from patients with primary biliary cirrhosis.
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pubmed:affiliation |
Tenovus Laboratory, and University Medicine, Southampton University Hospitals, UK. rkt@soton.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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