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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1998-5-7
|
| pubmed:abstractText |
Virtually all individuals with Down syndrome (DS) have neuropathologic changes characteristic of Alzheimer's disease (AD) beginning at 40 years of age. Few studies have examined factors that influence age at onset of AD in DS. We investigated whether sex differences in age at onset and risk of AD among adults with DS are similar to those observed in the general population and whether the effect of sex on risk of AD is modified by apolipoprotein E (APOE) genotype.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0028-3878
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
50
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
991-5
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:9566384-Adult,
pubmed-meshheading:9566384-Age of Onset,
pubmed-meshheading:9566384-Aged,
pubmed-meshheading:9566384-Alzheimer Disease,
pubmed-meshheading:9566384-Apolipoprotein E4,
pubmed-meshheading:9566384-Apolipoproteins E,
pubmed-meshheading:9566384-Down Syndrome,
pubmed-meshheading:9566384-Female,
pubmed-meshheading:9566384-Genotype,
pubmed-meshheading:9566384-Humans,
pubmed-meshheading:9566384-Male,
pubmed-meshheading:9566384-Middle Aged,
pubmed-meshheading:9566384-Risk Factors,
pubmed-meshheading:9566384-Sex Distribution
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Earlier onset of Alzheimer's disease in men with Down syndrome.
|
| pubmed:affiliation |
NYS Institute for Basic Research in Developmental Disabilities, Staten Island, NY 10314, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|