rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
1998-6-19
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pubmed:databankReference |
|
pubmed:abstractText |
The S100 family consists of small acidic proteins, belonging to the EF-hand class of calcium-binding proteins. They are primarily regulatory proteins, involved in cell growth, cell structure regulation and signal transduction. Psoriasin (S100A7) is an 11.7 kDa protein that is highly upregulated in the epidermis of patients suffering from the chronic skin disease psoriasis. Although its exact function is not known, psoriasin is believed to participate in the biochemical response which follows transient changes in the cellular Ca2+ concentration.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0969-2126
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
6
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
477-89
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:9562557-Calcium,
pubmed-meshheading:9562557-Calcium-Binding Proteins,
pubmed-meshheading:9562557-Dimerization,
pubmed-meshheading:9562557-Epidermis,
pubmed-meshheading:9562557-Holmium,
pubmed-meshheading:9562557-Humans,
pubmed-meshheading:9562557-Lanthanum,
pubmed-meshheading:9562557-Models, Molecular,
pubmed-meshheading:9562557-Molecular Sequence Data,
pubmed-meshheading:9562557-Protein Conformation,
pubmed-meshheading:9562557-Protein Structure, Secondary,
pubmed-meshheading:9562557-Psoriasis,
pubmed-meshheading:9562557-S100 Proteins,
pubmed-meshheading:9562557-Scattering, Radiation,
pubmed-meshheading:9562557-Sequence Alignment
|
pubmed:year |
1998
|
pubmed:articleTitle |
EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing.
|
pubmed:affiliation |
Macromolecular Crystallography, Aarhus University, Gustav Wieds Vej 10c, DK-8000, Aarhus C, Denmark.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|