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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1998-7-10
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pubmed:abstractText |
Distance geometry methods allow protein structures to be constructed using a large number of distance constraints, which can be elucidated by experimental techniques such as NMR. New methods for gleaning tertiary structural information from multiple sequence alignments make it possible for distance constraints to be predicted from sequence information alone. The basic distance geometry method can thus be applied using these empirically derived distance constraints. Such an approach, which incorporates a novel combinatoric procedure, is reported here.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1359-0278
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
149-60
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9562545-Amino Acid Sequence,
pubmed-meshheading:9562545-Binding Sites,
pubmed-meshheading:9562545-Computer Simulation,
pubmed-meshheading:9562545-Disulfides,
pubmed-meshheading:9562545-Evaluation Studies as Topic,
pubmed-meshheading:9562545-Forecasting,
pubmed-meshheading:9562545-Models, Molecular,
pubmed-meshheading:9562545-Molecular Sequence Data,
pubmed-meshheading:9562545-Protein Folding,
pubmed-meshheading:9562545-Protein Structure, Secondary,
pubmed-meshheading:9562545-Protein Structure, Tertiary,
pubmed-meshheading:9562545-Surface Properties
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pubmed:year |
1998
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pubmed:articleTitle |
A combinatorial distance-constraint approach to predicting protein tertiary models from known secondary structure.
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pubmed:affiliation |
Computational Chemistry Group, Universitätstrasse 16, ETH Zentrum, Zürich, CH 8092, Switzerland. gareth.chelva@anu.edu.au
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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