9561947

Source:http://linkedlifedata.com/resource/pubmed/id/9561947

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0001554, umls-concept:C0009450, umls-concept:C0009566, umls-concept:C0521116, umls-concept:C0556025, umls-concept:C1273870, umls-concept:C1550587
pubmed:issue	2
pubmed:dateCreated	1998-6-16
pubmed:abstractText	The diagnosis and management of infectious complications associated with injection drug use (IDU) are among some of the more challenging aspects of working with substance abusing populations. As the population of injection drug users age, we expect the number and severity of these complications to increase. Commonly seen infections, such as bacterial endocarditis and bacterial infections of bones, joints, and soft tissue, are now frequently complicated by concurrent immunodeficiency. Parenterally and sexually transmitted viral hepatitis is responsible for significant IDU morbidity and mortality. The human leukemia/lymphoma virus types I and II are increasing in prevalence in the IDU with uncertain long-term clinical effects. Immune dysfunction has been described in the IDU for decades, but the impact of host immune compromise on the transmission and the course of HIV-1 has yet to be fully appreciated. The integration of the treatment of substance abuse and its concurrent psychiatric disorders with the management of infectious complications, including immunodeficiency, promises to improve patient compliance with possible savings of overall medical costs.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8500909
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:issn	0740-5472
pubmed:author	pubmed-author:ContoreggiCC, pubmed-author:LangeW RWR, pubmed-author:RexroadV EVE
pubmed:issnType	Print
pubmed:volume	15
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	95-106
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:9561947-Humans, pubmed-meshheading:9561947-Infection, pubmed-meshheading:9561947-Substance Abuse, Intravenous
pubmed:articleTitle	Current management of infectious complications in the injecting drug user.
pubmed:affiliation	Division of Intramural Research, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD 21224, USA. ccontore@irp.nida.nih.gov
pubmed:publicationType	Journal Article, Research Support, U.S. Gov't, P.H.S., Review