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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-6-3
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pubmed:abstractText |
Sarcoidal granulomas are found in sarcoidosis and in reactions to foreign materials. We report the case of an 81-year-old woman with glaucoma who presented with multiple brown-black asymptomatic papules over the chin and involving nasal mucosa and columella of 1-year duration. Biopsy of the nasal mucosa and cutaneous papules showed sarcoidal granulomas associated with brown-black intracellular pigment within multinucleated giant cells. Electron-probe x-ray microanalysis demonstrated high sulfur content. Clinical studies showed no evidence of systemic sarcoidosis. Two of three ophthalmologic drops contained sodium bisulfite; bisulfite is known to cause allergic reactions. Although the exact substance causing the granulomatous reaction is unknown, the distribution of the lesions--nasal mucosa and columella (via the nasal lacrimal duct) and the underlying chin--implicate the eyedrops in the production of the pigmented granulomatous nodules.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0193-1091
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
175-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9557788-Aged,
pubmed-meshheading:9557788-Dermatitis,
pubmed-meshheading:9557788-Electron Probe Microanalysis,
pubmed-meshheading:9557788-Female,
pubmed-meshheading:9557788-Granuloma, Foreign-Body,
pubmed-meshheading:9557788-Humans,
pubmed-meshheading:9557788-Nasal Mucosa,
pubmed-meshheading:9557788-Ophthalmic Solutions,
pubmed-meshheading:9557788-Sarcoidosis,
pubmed-meshheading:9557788-Skin,
pubmed-meshheading:9557788-Sulfur
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pubmed:year |
1998
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pubmed:articleTitle |
Sarcoidal foreign-body granulomatous dermatitis associated with ophthalmic drops.
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pubmed:affiliation |
Division of Dermatopathology, Albany Medical College, New York 12208, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
|