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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1998-4-30
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pubmed:abstractText |
Subclavian artery stenosis is found in up to 25% of supraaortic lesions. Bypass grafting is the procedure of choice but controversies exist concerning the optimal technique and the effect of postoperative antithrombotic therapy on long-term patency. The authors retrospectively analyzed 40 patients with carotid-subclavian bypasses. Stenoses were documented preoperatively by arteriography. Patency was determined by clinical, ultrasound, or arteriographic examinations. Cumulative patency rates were calculated by Kaplan-Meier method and analyzed by Tarone-Ware test. Graft materials were Dacron (32), polytetrafluoroethylene (seven) or saphenous vein (one). Indications for surgery included vertebrobasilar insufficiency (22.5%), upper extremity ischemia (22.5%), and the combination of both (55.0%). Perioperative mortality and morbidity were 2.5% and 10.0%, respectively. Patients were followed up from 0 to 134 months (mean 61+/-39 months). Cumulative 5-year patency rate was 83.3%. Anticoagulation with acetylsalicylic acid (ASA) led to significantly better 5-year patency rates (100%) as compared with the combination of ASA and dipyridamole (64.0%, p=0.013) or no anticoagulation (70.0%, p=0.016). Carotid-subclavian bypass led to excellent long-term patency rates and can provide durable relief of symptoms with minimal perioperative morbidity and mortality. Therefore, it is a worthwhile procedure to correct proximal subclavian artery stenosis. Postoperative medication with ASA seems to increase long-term bypass function significantly.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anticoagulants,
http://linkedlifedata.com/resource/pubmed/chemical/Aspirin,
http://linkedlifedata.com/resource/pubmed/chemical/Dipyridamole,
http://linkedlifedata.com/resource/pubmed/chemical/Platelet Aggregation Inhibitors,
http://linkedlifedata.com/resource/pubmed/chemical/Polyethylene Terephthalates,
http://linkedlifedata.com/resource/pubmed/chemical/Polytetrafluoroethylene
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-3197
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
49
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
279-87
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9555931-Adult,
pubmed-meshheading:9555931-Aged,
pubmed-meshheading:9555931-Angiography,
pubmed-meshheading:9555931-Anticoagulants,
pubmed-meshheading:9555931-Arm,
pubmed-meshheading:9555931-Arterial Occlusive Diseases,
pubmed-meshheading:9555931-Aspirin,
pubmed-meshheading:9555931-Blood Vessel Prosthesis,
pubmed-meshheading:9555931-Blood Vessel Prosthesis Implantation,
pubmed-meshheading:9555931-Carotid Arteries,
pubmed-meshheading:9555931-Dipyridamole,
pubmed-meshheading:9555931-Female,
pubmed-meshheading:9555931-Follow-Up Studies,
pubmed-meshheading:9555931-Graft Occlusion, Vascular,
pubmed-meshheading:9555931-Humans,
pubmed-meshheading:9555931-Ischemia,
pubmed-meshheading:9555931-Longitudinal Studies,
pubmed-meshheading:9555931-Male,
pubmed-meshheading:9555931-Middle Aged,
pubmed-meshheading:9555931-Platelet Aggregation Inhibitors,
pubmed-meshheading:9555931-Polyethylene Terephthalates,
pubmed-meshheading:9555931-Polytetrafluoroethylene,
pubmed-meshheading:9555931-Prosthesis Design,
pubmed-meshheading:9555931-Retrospective Studies,
pubmed-meshheading:9555931-Saphenous Vein,
pubmed-meshheading:9555931-Subclavian Artery,
pubmed-meshheading:9555931-Vascular Patency,
pubmed-meshheading:9555931-Vertebrobasilar Insufficiency
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pubmed:year |
1998
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pubmed:articleTitle |
Carotid-subclavian bypass for subclavian artery revascularization: long-term follow-up and effect of antiplatelet therapy.
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pubmed:affiliation |
Surgical Center, Division of Cardiothoracic and Vascular Surgery, Hannover Medical School, Germany.
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pubmed:publicationType |
Journal Article
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