Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-4-30
pubmed:abstractText
Subclavian artery stenosis is found in up to 25% of supraaortic lesions. Bypass grafting is the procedure of choice but controversies exist concerning the optimal technique and the effect of postoperative antithrombotic therapy on long-term patency. The authors retrospectively analyzed 40 patients with carotid-subclavian bypasses. Stenoses were documented preoperatively by arteriography. Patency was determined by clinical, ultrasound, or arteriographic examinations. Cumulative patency rates were calculated by Kaplan-Meier method and analyzed by Tarone-Ware test. Graft materials were Dacron (32), polytetrafluoroethylene (seven) or saphenous vein (one). Indications for surgery included vertebrobasilar insufficiency (22.5%), upper extremity ischemia (22.5%), and the combination of both (55.0%). Perioperative mortality and morbidity were 2.5% and 10.0%, respectively. Patients were followed up from 0 to 134 months (mean 61+/-39 months). Cumulative 5-year patency rate was 83.3%. Anticoagulation with acetylsalicylic acid (ASA) led to significantly better 5-year patency rates (100%) as compared with the combination of ASA and dipyridamole (64.0%, p=0.013) or no anticoagulation (70.0%, p=0.016). Carotid-subclavian bypass led to excellent long-term patency rates and can provide durable relief of symptoms with minimal perioperative morbidity and mortality. Therefore, it is a worthwhile procedure to correct proximal subclavian artery stenosis. Postoperative medication with ASA seems to increase long-term bypass function significantly.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-3197
pubmed:author
pubmed:issnType
Print
pubmed:volume
49
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
279-87
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed-meshheading:9555931-Adult, pubmed-meshheading:9555931-Aged, pubmed-meshheading:9555931-Angiography, pubmed-meshheading:9555931-Anticoagulants, pubmed-meshheading:9555931-Arm, pubmed-meshheading:9555931-Arterial Occlusive Diseases, pubmed-meshheading:9555931-Aspirin, pubmed-meshheading:9555931-Blood Vessel Prosthesis, pubmed-meshheading:9555931-Blood Vessel Prosthesis Implantation, pubmed-meshheading:9555931-Carotid Arteries, pubmed-meshheading:9555931-Dipyridamole, pubmed-meshheading:9555931-Female, pubmed-meshheading:9555931-Follow-Up Studies, pubmed-meshheading:9555931-Graft Occlusion, Vascular, pubmed-meshheading:9555931-Humans, pubmed-meshheading:9555931-Ischemia, pubmed-meshheading:9555931-Longitudinal Studies, pubmed-meshheading:9555931-Male, pubmed-meshheading:9555931-Middle Aged, pubmed-meshheading:9555931-Platelet Aggregation Inhibitors, pubmed-meshheading:9555931-Polyethylene Terephthalates, pubmed-meshheading:9555931-Polytetrafluoroethylene, pubmed-meshheading:9555931-Prosthesis Design, pubmed-meshheading:9555931-Retrospective Studies, pubmed-meshheading:9555931-Saphenous Vein, pubmed-meshheading:9555931-Subclavian Artery, pubmed-meshheading:9555931-Vascular Patency, pubmed-meshheading:9555931-Vertebrobasilar Insufficiency
pubmed:year
1998
pubmed:articleTitle
Carotid-subclavian bypass for subclavian artery revascularization: long-term follow-up and effect of antiplatelet therapy.
pubmed:affiliation
Surgical Center, Division of Cardiothoracic and Vascular Surgery, Hannover Medical School, Germany.
pubmed:publicationType
Journal Article