Linked Life Data

9552370

Source:http://linkedlifedata.com/resource/pubmed/id/9552370

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1998-4-30
pubmed:abstractText
The chapter reviews the structure and function of the nuclear envelope and describes its dynamic structural changes during cell cycle. Particular emphasis is placed on the regulation of mitotic nuclear envelope breakdown (NEBD), the process by which the physical barrier between cytoplasm and nucleus is dissolved to allow for cell division. The literature suggesting the involvement of multiple protein kinases in NEBD is reviewed and evidence is presented that multiple mitotic lamin kinases, including p34cdc2/cyclin B kinase and protein kinase C, play key roles in mitotic nuclear lamina disassembly. Finally, a model for regulation of mitotic nuclear lamina disassembly by multi-site phosphorylation is described.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1087-2957
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
271-86
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1995
pubmed:articleTitle
The regulation of mitotic nuclear envelope breakdown: a role for multiple lamin kinases.
pubmed:affiliation
Sealy Center for Oncology, University of Texas Medical Branch, Galveston 77555-1048, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Review, Research Support, Non-U.S. Gov't