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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1998-4-23
|
| pubmed:abstractText |
Over a one-year period, all coagulase-negative staphylococci (CoNS) from blood cultures, cerebrospinal fluids and peritoneal effluents from patients in a major Danish university hospital were investigated for susceptibility to penicillin G; methicillin; gentamicin; netilmicin; amikacin; erythromycin; clindamycin; fusidic acid; rifampicin; tetracycline; chloramphenicol; ciprofloxacin; teicoplanin; and vancomycin. Among the CoNS-isolates, 56% were resistant to methicillin, 51% to gentamicin, 28% to ciprofloxacin, and 5% to teicoplanin. Blood culture CoNS-isolates from patients with a central venous catheter (CVC) were more often resistant to various antibiotics compared to CoNS-isolates from patients without a CVC, e.g. methicillin (72% vs 21%), gentamicin (65% vs 22%) (p<0.00000001). Great diversity in antibiotic resistance between the wards was found; methicillin resistance (in most cases multiple antibiotic resistance) was in particular associated with consumption of broad-spectrum beta-lactams, quinolones, and total antibiotic consumption in a ward. Thus, the antibiotic policy of a ward is an important factor for antibiotic resistance among CoNS.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0903-4641
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
106
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
411-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:9548431-Coagulase,
pubmed-meshheading:9548431-Drug Resistance, Microbial,
pubmed-meshheading:9548431-Female,
pubmed-meshheading:9548431-Hospitals, University,
pubmed-meshheading:9548431-Humans,
pubmed-meshheading:9548431-Male,
pubmed-meshheading:9548431-Microbial Sensitivity Tests,
pubmed-meshheading:9548431-Staphylococcus
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Coagulase-negative staphylococci in a major Danish university hospital: diversity in antibiotic susceptibility between wards.
|
| pubmed:affiliation |
Department of Clinical Microbiology, The National University Hospital (Rigshospitalet), Copenhagen, Denmark.
|
| pubmed:publicationType |
Journal Article
|