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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1998-5-15
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pubmed:abstractText |
A fluorescence polarization immunoassay for barbiturates on the Abbott AxSYM analyzer is described. The assay displayed dilution linearity up to 1200 ng/mL; coefficients of variation varied from 5.96 to 8.61%; recovery varied from 94.9 to 105.3%; and sensitivity was less than 40 ng/mL. Good correlation between the standard six- and factory two-point calibration methods was observed. The Immunoassay demonstrated good cross-reactivity to several commonly prescribed barbiturates; low cross-reactivity with structurally similar compounds; low interference from endogenous substances, dyes, preservatives, and several commonly available adulterants; and good correlation with the TDx Barbiturate Urine assay.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0146-4760
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
105-11
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9547406-Autoanalysis,
pubmed-meshheading:9547406-Drug Contamination,
pubmed-meshheading:9547406-Drug Evaluation, Preclinical,
pubmed-meshheading:9547406-Fluorescence Polarization Immunoassay,
pubmed-meshheading:9547406-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:9547406-Humans,
pubmed-meshheading:9547406-Hypnotics and Sedatives,
pubmed-meshheading:9547406-Reproducibility of Results,
pubmed-meshheading:9547406-Sensitivity and Specificity,
pubmed-meshheading:9547406-Substance Abuse Detection
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pubmed:articleTitle |
A barbiturate screening assay for the Abbott AxSYM analyzer.
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pubmed:affiliation |
Department of Chemistry, Abbott Laboratories, Abbott Park, Illinois 60064-3500, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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