| pubmed-article:9546254 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9546254 | lifeskim:mentions | umls-concept:C0599779 | lld:lifeskim |
| pubmed-article:9546254 | lifeskim:mentions | umls-concept:C0460004 | lld:lifeskim |
| pubmed-article:9546254 | lifeskim:mentions | umls-concept:C0011900 | lld:lifeskim |
| pubmed-article:9546254 | lifeskim:mentions | umls-concept:C0940937 | lld:lifeskim |
| pubmed-article:9546254 | lifeskim:mentions | umls-concept:C0242506 | lld:lifeskim |
| pubmed-article:9546254 | pubmed:issue | 4 Pt 1 | lld:pubmed |
| pubmed-article:9546254 | pubmed:dateCreated | 1998-4-30 | lld:pubmed |
| pubmed-article:9546254 | pubmed:abstractText | Laser-induced fluorescence (LIF) of tissues depends on their biochemical and histomorphologic characteristics. LIF spectroscopic properties of 9,10-dimethyl-1,2-benzanthracene (DMBA)-induced precancerous and early cancerous lesions in a hamster buccal pouch mucosa model were studied. Fluorescence spectra from neoplastic lesions showed a characteristic fluorescence peak in the red region of the visible spectrum centered between 630 and 640 nm when excited with 410-nm light. Using this as a diagnostic criterion, 45 of 49 lesions studied were correctly diagnosed, including early dysplastic lesions. Follow-up study of four dysplastic lesions over 2 weeks revealed an increase in red fluorescence intensity. The findings of these experiments suggest that LIF spectroscopy may be a valuable noninvasive technique not only for early diagnosis of head and neck cancer, but also to probe a possible biochemical surrogate biomarker in the follow-up of suspected lesions. | lld:pubmed |
| pubmed-article:9546254 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9546254 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9546254 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9546254 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:9546254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9546254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9546254 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9546254 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9546254 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:9546254 | pubmed:issn | 0023-852X | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:ShapshayS MSM | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:DiazII | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:McMillanKK | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:ZhangXX | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:ManoharanRR | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:KabaniSS | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:ItzkanII | lld:pubmed |
| pubmed-article:9546254 | pubmed:author | pubmed-author:DhingraJ KJK | lld:pubmed |
| pubmed-article:9546254 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9546254 | pubmed:volume | 108 | lld:pubmed |
| pubmed-article:9546254 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9546254 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9546254 | pubmed:pagination | 471-5 | lld:pubmed |
| pubmed-article:9546254 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:9546254 | pubmed:meshHeading | pubmed-meshheading:9546254-... | lld:pubmed |
| pubmed-article:9546254 | pubmed:meshHeading | pubmed-meshheading:9546254-... | lld:pubmed |
| pubmed-article:9546254 | pubmed:meshHeading | pubmed-meshheading:9546254-... | lld:pubmed |
| pubmed-article:9546254 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9546254 | pubmed:articleTitle | Diagnosis of head and neck precancerous lesions in an animal model using fluorescence spectroscopy. | lld:pubmed |
| pubmed-article:9546254 | pubmed:affiliation | Department of Otolaryngology Head and Neck Surgery, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA. | lld:pubmed |
| pubmed-article:9546254 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9546254 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9546254 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:9546254 | lld:pubmed |
