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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1998-4-21
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pubmed:abstractText |
A patient with multiple myeloma was noted to have an IgA deficiency during investigation of a possible transfusion reaction due to IgA deficiency and anti-IgA. Because of the patient's age, otherwise good health, and early stage of disease, he was enrolled in a research treatment protocol that involved an allogeneic bone marrow transplant (BMT). The BMT successfully put the patient in complete remission from his multiple myeloma and corrected his IgA deficiency. Class-specific IgG anti-IgA antibody that had been identified prior to BMT was no longer detectable in his plasma. Anaphylactic transfusion reactions were successfully avoided by using a combination of IgA-deficient and washed blood components including the marrow graft, and IgA-reduced intravenous immunoglobulin.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0361-8609
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
57
|
pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
326-30
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9544978-Adult,
pubmed-meshheading:9544978-Antibodies, Anti-Idiotypic,
pubmed-meshheading:9544978-Blood Transfusion,
pubmed-meshheading:9544978-Bone Marrow Transplantation,
pubmed-meshheading:9544978-Humans,
pubmed-meshheading:9544978-IgA Deficiency,
pubmed-meshheading:9544978-Immunoglobulin A,
pubmed-meshheading:9544978-Male,
pubmed-meshheading:9544978-Multiple Myeloma
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pubmed:year |
1998
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pubmed:articleTitle |
Transfusion management of an IgA deficient patient with anti-IgA and incidental correction of IgA deficiency after allogeneic bone marrow transplantation.
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pubmed:affiliation |
Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425, USA.
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pubmed:publicationType |
Journal Article,
Case Reports
|