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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-6-8
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pubmed:abstractText |
The aim of the present study was to use a combination of the reverse transcription-polymerase chain reaction and a new diagnostic test for antibodies against the viral envelope protein E2 to assess the prevalence of hepatitis G virus (GBV-C/HGV) infection in sera of Hungarian children on hemodialysis (HD) or peritoneal dialysis (CAPD), as well as in sera of renal transplant patients (RTx). The GBV-C/HGV RNA prevalence was significantly higher in the whole group of children with renal failure (18.5%) than in the control group (children with urinary tract infection, 2.5%). The difference between the GBV-C/HGV RNA prevalence in the RTx group (33.3%) and in the control group (2.5%) was significant (P = 0.007). Anti-E2, which is considered an indicator of a past GBV-C/ HGV infection, was detected in 10% (1/10) of HD patients, in 33.3% (4/12) of RTx patients, but in none of the children on CAPD. These differences were not significant. Children receiving a renal graft are at an increased risk of developing GBV-C/HGV infection, which may be attributed to the immunosuppressive drugs necessary to maintain the grafts.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0931-041X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
93-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9543362-Adolescent,
pubmed-meshheading:9543362-Adult,
pubmed-meshheading:9543362-Antibodies, Viral,
pubmed-meshheading:9543362-Child,
pubmed-meshheading:9543362-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9543362-Female,
pubmed-meshheading:9543362-Flaviviridae,
pubmed-meshheading:9543362-Hepatitis, Viral, Human,
pubmed-meshheading:9543362-Humans,
pubmed-meshheading:9543362-Hungary,
pubmed-meshheading:9543362-Kidney Transplantation,
pubmed-meshheading:9543362-Male,
pubmed-meshheading:9543362-Peritoneal Dialysis, Continuous Ambulatory,
pubmed-meshheading:9543362-Polymerase Chain Reaction
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pubmed:year |
1998
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pubmed:articleTitle |
Hepatitis G virus infection in children on dialysis and after renal transplantation.
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pubmed:affiliation |
Department of Nephrology, University Hospital Essen, Germany.
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pubmed:publicationType |
Journal Article,
Clinical Trial
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