Linked Life Data

954241

Source:http://linkedlifedata.com/resource/pubmed/id/954241

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-10-29
pubmed:abstractText
Platelet function studies were performed on 18 patients with end stage chronic renal failure receiving treatment by long-term peritoneal dialysis. The results of these studies were compared with previously reported data on healthy volunteers, non-dialyzed patients with chronic renal failure and patients treated by hemodialysis. Platelet adhesiveness was impaired and, unlike the other patient groups, there was no relationship between adhesiveness and serum creatinine. Platelet aggregation to both ADP and adrenaline chloride was normal, whereas marked impairment was seen in non-dialyzed patients with severe chronic renal failure and patients receiving hemodialysis. The results suggest that different uremic retention products affect these different phases in the platelet adhesion-aggregation reaction and that the peritoneal membrane is more permeable to that dialyzable factor which inhibits aggregation than conventional hemodialysis membranes. The studies are of interest both in consideration of adequacy of dialysis and in studies into the nature of the platelet defect in uremia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0301-0430
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
335-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1976
pubmed:articleTitle
Platelet function in patients on long term peritoneal dialysis.
pubmed:publicationType
Journal Article, Comparative Study