Linked Life Data

9539451

Source:http://linkedlifedata.com/resource/pubmed/id/9539451

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-6-1
pubmed:abstractText
Effect of flanking quantitative trait loci (QTL)-marker bracket size on genetic response to marker assisted selection in an outbred population was studied by simulation of a nucleus breeding scheme. In addition, genetic response with marker assisted selection (MAS) from two quantitative trait loci on the same and different chromosome(s) was investigated. QTL that explained either 5% or 10% of phenotypic variance were simulated. A polygenic component was simulated in addition to the quantitative trait loci. In total, 35% of the phenotypic variance was due to genetic factors. The trait was measured on females only. Having smaller marker brackets flanking the QTL increased the genetic response from MAS selection. This was due to the greater ability to trace the QTL transmission from one generation to the next with the smaller flanking QTL-marker bracket, which increased the accuracy of estimation of the QTL allelic effects. Greater negative covariance between effects at both QTL was observed when two QTL were located on the same chromosome compared to different chromosomes. Genetic response with MAS was greater when the QTL were on the same chromosome in the early generations and greater when they were on different chromosomes in the later generations of MAS.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-1500565, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-16718932, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-1968875, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-2258496, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-7203003, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-7713441, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-7813903, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8056319, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8134840, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8206366, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8575670, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8899535, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8908510, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8913761, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-8978065, http://linkedlifedata.com/resource/pubmed/commentcorrection/9539451-9436122
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
148
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1389-96
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Genetic response from marker assisted selection in an outbred population for differing marker bracket sizes and with two identified quantitative trait loci.
pubmed:affiliation
Department of Animal Breeding, Wageningen Institute of Animal Sciences, Wageningen Agricultural University, The Netherlands. r.j.spelman@massey.ac.nz
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't