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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1998-4-7
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pubmed:abstractText |
The question whether nitric oxide protects or impairs organ perfusion during early endotoxemia has not been completely answered. To evaluate the regulative function of nitric oxide on organ microvascular perfusion and leukocyte accumulation during endotoxemia, we studied the influence of a non-selective nitric oxide inhibitor and a preferential inducible nitric oxide synthase inhibitor (respectively, N(G)-nitro-L-arginine methyl ester and aminoethyl-isothiourea) on liver microcirculation (intravital fluorescence microscopy) in a rat model.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0168-8278
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
61-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9537865-Animals,
pubmed-meshheading:9537865-Endotoxemia,
pubmed-meshheading:9537865-Enzyme Inhibitors,
pubmed-meshheading:9537865-Liver Circulation,
pubmed-meshheading:9537865-Male,
pubmed-meshheading:9537865-Microcirculation,
pubmed-meshheading:9537865-Microscopy, Fluorescence,
pubmed-meshheading:9537865-NG-Nitroarginine Methyl Ester,
pubmed-meshheading:9537865-Nitric Oxide Synthase,
pubmed-meshheading:9537865-Nitric Oxide Synthase Type II,
pubmed-meshheading:9537865-Rats,
pubmed-meshheading:9537865-Rats, Sprague-Dawley,
pubmed-meshheading:9537865-Time Factors,
pubmed-meshheading:9537865-beta-Aminoethyl Isothiourea
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pubmed:year |
1998
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pubmed:articleTitle |
Effects of the nitric oxide synthase inhibitors N(G)-nitro-L-arginine methyl ester and aminoethyl-isothiourea on the liver microcirculation in rat endotoxemia.
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pubmed:affiliation |
Institute for Surgical Research, Munich University, Germany. corso@icf.med.uni-muenchen.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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