|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
11
|
|
pubmed:dateCreated |
1998-4-9
|
|
pubmed:abstractText |
Angiopoietin-2 is a new member of the family of the ligands of Tek (Tie2), a transmembrane receptor with tyrosine kinase activity which is specifically expressed in endothelial cells during angiogenesis. Several lines of evidence indicate that angiopoietin-1 is involved in pericyte recruitment by endothelial cells and in the maintenance of cell-cell and cell matrix association in mature capillaries. Angiopoietin-2 behaves as an antagonist of angiopoietin-1. It is suggested that it looses capillary structure and renders endothelial cells to become responsive to angiogenic stimuli.
|
|
pubmed:language |
fre
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Nov
|
|
pubmed:issn |
0007-4551
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
84
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1079-80
|
|
pubmed:dateRevised |
2009-11-19
|
|
pubmed:meshHeading |
pubmed-meshheading:9536990-Angiopoietin-2,
pubmed-meshheading:9536990-Endothelium, Vascular,
pubmed-meshheading:9536990-Enzyme Inhibitors,
pubmed-meshheading:9536990-Humans,
pubmed-meshheading:9536990-Neovascularization, Physiologic,
pubmed-meshheading:9536990-Proteins,
pubmed-meshheading:9536990-Receptor Protein-Tyrosine Kinases,
pubmed-meshheading:9536990-Receptors, Growth Factor,
pubmed-meshheading:9536990-Receptors, Vascular Endothelial Growth Factor
|
|
pubmed:year |
1997
|
|
pubmed:articleTitle |
[Angiopoietin-2, a new molecular actor involved in vascular tree morphogenesis].
|
|
pubmed:affiliation |
CNRS EP560, Institut Pasteur de Lille.
|
|
pubmed:publicationType |
Journal Article,
English Abstract
|
