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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
1998-4-9
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pubmed:abstractText |
A substantial proportion of cases of glaucoma have a genetic basis. Mutations causing glaucoma have been identified in the chromosome 1 open-angle glaucoma gene (GLC1A), which encodes a 57-kd protein known as myocilin. The normal role of this protein and the mechanism by which mutations cause glaucoma are not known.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0028-4793
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pubmed:author |
pubmed-author:AlwardW LWL,
pubmed-author:CooteM AMA,
pubmed-author:DurcanF JFJ,
pubmed-author:FingertJ HJH,
pubmed-author:JohnsonA TAT,
pubmed-author:JunquaDD,
pubmed-author:LernerS FSF,
pubmed-author:MackenD LDL,
pubmed-author:McCartneyP JPJ,
pubmed-author:SheffieldV CVC,
pubmed-author:StoneE MEM
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pubmed:issnType |
Print
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pubmed:day |
9
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pubmed:volume |
338
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1022-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:9535666-Age of Onset,
pubmed-meshheading:9535666-Aged,
pubmed-meshheading:9535666-Case-Control Studies,
pubmed-meshheading:9535666-Chromosomes, Human, Pair 1,
pubmed-meshheading:9535666-Cytoskeletal Proteins,
pubmed-meshheading:9535666-Eye Proteins,
pubmed-meshheading:9535666-Female,
pubmed-meshheading:9535666-Glaucoma, Open-Angle,
pubmed-meshheading:9535666-Glycoproteins,
pubmed-meshheading:9535666-Humans,
pubmed-meshheading:9535666-Lod Score,
pubmed-meshheading:9535666-Male,
pubmed-meshheading:9535666-Mutation
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pubmed:year |
1998
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pubmed:articleTitle |
Clinical features associated with mutations in the chromosome 1 open-angle glaucoma gene (GLC1A)
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pubmed:affiliation |
Department of Ophthalmology, University of Iowa, Iowa City 52242, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Multicenter Study
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