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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1998-4-21
|
| pubmed:abstractText |
To determine whether Epstein-Barr virus (EBV) constitutes a contributing factor in AIDS and, conversely, whether the human immunodeficiency virus (HIV) alters the course of primary EBV infection in a pediatric population, 62 children born to HIV-infected mothers and prospectively followed were evaluated. EBV infection was documented by EBV-specific serology and polymerase chain reaction and by clinical history. HIV infection status was determined according to the Centers for Disease Control and Prevention pediatric classification system. Demographics from HIV-infected and HIV-uninfected children were comparable. The data suggest that HIV-infected children may acquire primary EBV infection earlier in life. The incidence of accompanying splenomegaly or hepatomegaly (or both) around the time of EBV seroconversion was higher among HIV-infected children than among HIV-uninfected children. In contrast, HIV disease progression and HIV-1 RNA load did not seem to be influenced by primary EBV infection.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0022-1899
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
177
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1087-90
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9534989-AIDS-Related Opportunistic Infections,
pubmed-meshheading:9534989-Antibodies, Viral,
pubmed-meshheading:9534989-Capsid,
pubmed-meshheading:9534989-DNA, Viral,
pubmed-meshheading:9534989-Female,
pubmed-meshheading:9534989-HIV-1,
pubmed-meshheading:9534989-Hepatomegaly,
pubmed-meshheading:9534989-Herpesviridae Infections,
pubmed-meshheading:9534989-Herpesvirus 4, Human,
pubmed-meshheading:9534989-Humans,
pubmed-meshheading:9534989-Incidence,
pubmed-meshheading:9534989-Infant,
pubmed-meshheading:9534989-Infant, Newborn,
pubmed-meshheading:9534989-Male,
pubmed-meshheading:9534989-Polymerase Chain Reaction,
pubmed-meshheading:9534989-Pregnancy,
pubmed-meshheading:9534989-Pregnancy Complications, Infectious,
pubmed-meshheading:9534989-Prospective Studies,
pubmed-meshheading:9534989-RNA, Viral,
pubmed-meshheading:9534989-Splenomegaly,
pubmed-meshheading:9534989-Tumor Virus Infections,
pubmed-meshheading:9534989-Viral Load
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Natural history of Epstein-Barr virus infection in a prospective pediatric cohort born to human immunodeficiency virus-infected mothers.
|
| pubmed:affiliation |
Department of Microbiology and Infectious Diseases, Research Center, and Centre Maternel et Infantile sur le SIDA, Hôpital Sainte-Justine, Montréal, Canada. LP88709@glaxowellcome.com
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|