rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
3
|
pubmed:dateCreated |
1998-4-24
|
pubmed:abstractText |
Patients with familial combined hyperlipidemia (FCH) have an increased cardiovascular mortality despite only moderate elevations of LDL-cholesterol. Since endothelial NO release is intimately involved in the anti-atherosclerotic effects of the endothelium, we studied the effect of short-term lipid-lowering therapy on NO-mediated vasodilatation in patients with FCH. In view of only moderate LDL elevations, we evaluated whether alterations in other lipid fractions upon therapy correlated to changes in NO-mediated vasodilatation.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Dec
|
pubmed:issn |
0008-6363
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
36
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
445-52
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:9534865-Adult,
pubmed-meshheading:9534865-Arginine,
pubmed-meshheading:9534865-Cholesterol,
pubmed-meshheading:9534865-Endothelium, Vascular,
pubmed-meshheading:9534865-Forearm,
pubmed-meshheading:9534865-Humans,
pubmed-meshheading:9534865-Hyperlipoproteinemia Type II,
pubmed-meshheading:9534865-Hypolipidemic Agents,
pubmed-meshheading:9534865-Lipoproteins,
pubmed-meshheading:9534865-Male,
pubmed-meshheading:9534865-Middle Aged,
pubmed-meshheading:9534865-Nitric Oxide,
pubmed-meshheading:9534865-Nitroprusside,
pubmed-meshheading:9534865-Regional Blood Flow,
pubmed-meshheading:9534865-Serotonin,
pubmed-meshheading:9534865-Simvastatin,
pubmed-meshheading:9534865-Vasodilation
|
pubmed:year |
1997
|
pubmed:articleTitle |
NO activity in familial combined hyperlipidemia: potential role of cholesterol remnants.
|
pubmed:affiliation |
Department of Nephrology and Hypertension, University Hospital Utrecht, The Netherlands.
|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|