Linked Life Data

9533873

Source:http://linkedlifedata.com/resource/pubmed/id/9533873

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-5-29
pubmed:abstractText
The critical point hypothesis explains the origin of some cardiac arrhythmias, and the bidomain model describes electrical stimulation of the heart. In this paper, the critical point hypothesis is combined with the bidomain model. The result is four new predictions about the pinwheel experiment, a fundamental experiment in cardiac electrophysiology. These are: (1) The duration of the vulnerable period during cathodal S2 stimulation is longer for an S1 wavefront propagating perpendicular to the fibers than for an S1 wavefront propagating parallel to the fibers. (2) For anodal S2 stimulation with the S1 wavefront propagating parallel to the fibers, the vulnerable period splits into two periods with an "invulnerable period" between them. (3) For anodal S2 stimulation with the S1 wavefront propagating perpendicular to the fibers, the vulnerable period consists of only one period. (4) A previously suggested mechanism for the upper limit of vulnerability (S2 is so strong that the entire tissue is depolarized by an amount greater than S*) is no longer applicable.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-5193
pubmed:author
pubmed:copyrightInfo
Copyright 1998 Academic Press Limited.
pubmed:issnType
Print
pubmed:day
21
pubmed:volume
190
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
389-93
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
The pinwheel experiment revisited.
pubmed:affiliation
Department of Physics & Astronomy, Vanderbilt University, Box 1807, Station B, Nashville, TN 37235, USA. roth@compsci.cas.vanderbilt.edu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't