Linked Life Data

9533781

Source:http://linkedlifedata.com/resource/pubmed/id/9533781

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1998-4-10
pubmed:abstractText
The process of skeletal muscle repair was investigated by immunocytochemical evaluation of chicken leg muscles injured by a localized crush or superficial cut. Only the damaged parts of the muscle fibers, approximately 400-500 microm across, along the longitudinal axis, expressed ventricular myosin heavy chain. The level of this myosin heavy chain along the fiber length further decreased with time. Unlike the newly generated independent regenerating myotubes, even the injured parts of original mature muscle fibers positive for ventricular myosin heavy chain in the immediate vicinity of injury did not show changes in the expression of slow or fast myosin heavy chains in these regions. It is concluded that muscle fibers injured by superficial cut or crush methods used in this study despite being multinucleated were rapidly repaired by localized changes without affecting the major gene expression in the uninjured parts of the fibers.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0148-639X
pubmed:author
pubmed:issnType
Print
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
469-81
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Localized and limited changes in the expression of myosin heavy chains in injured skeletal muscle fibers being repaired.
pubmed:affiliation
Department of Basic Sciences, The Royal Veterinary College, University of London, United Kingdom.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't