| pubmed-article:9528004 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C0521026 | lld:lifeskim |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C0282641 | lld:lifeskim |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C0043342 | lld:lifeskim |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C0017262 | lld:lifeskim |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C2911684 | lld:lifeskim |
| pubmed-article:9528004 | lifeskim:mentions | umls-concept:C0185117 | lld:lifeskim |
| pubmed-article:9528004 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:9528004 | pubmed:dateCreated | 1998-5-13 | lld:pubmed |
| pubmed-article:9528004 | pubmed:abstractText | Expression of transgenes within a single generation by direct DNA injection into vertebrate embryos has been plagued by inefficient and nonuniform gene expression. We report a novel strategy for efficient and stable expression of transgenes driven by both ubiquitous and tissue-specific promoters by direct DNA injection into developing Xenopus laevis embryos. This strategy involves flanking expression cassettes of interest with inverted terminal repeat sequences (ITRs) from adeno-associated virus. Our results suggest that the ITR strategy may be generally applicable to other systems, such as zebra fish and embryonic stem cells, and may enable tissue-specific expression of transgenes in problematic contexts. | lld:pubmed |
| pubmed-article:9528004 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9528004 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9528004 | pubmed:language | eng | lld:pubmed |
| pubmed-article:9528004 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:9528004 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:9528004 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:9528004 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:9528004 | pubmed:issn | 1087-0156 | lld:pubmed |
| pubmed-article:9528004 | pubmed:author | pubmed-author:WangYY | lld:pubmed |
| pubmed-article:9528004 | pubmed:author | pubmed-author:NEWM IMI | lld:pubmed |
| pubmed-article:9528004 | pubmed:author | pubmed-author:EvansS MSM | lld:pubmed |
| pubmed-article:9528004 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:9528004 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:9528004 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:9528004 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:9528004 | pubmed:pagination | 253-7 | lld:pubmed |
| pubmed-article:9528004 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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| pubmed-article:9528004 | pubmed:year | 1998 | lld:pubmed |
| pubmed-article:9528004 | pubmed:articleTitle | Viral sequences enable efficient and tissue-specific expression of transgenes in Xenopus. | lld:pubmed |
| pubmed-article:9528004 | pubmed:affiliation | Department of Medicine, University of California, San Diego, La Jolla 92093-0613, USA. | lld:pubmed |
| pubmed-article:9528004 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:9528004 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:9528004 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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