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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
|
pubmed:dateCreated |
1998-5-1
|
pubmed:abstractText |
Aberrant expression of TGF-beta and/or receptor/signaling function is present in a wide variety of disease processes. Overexpression of TGF-beta isoforms in transgenic mice using tissue-specific promoters has provided model systems to study the effects of increased activity of TGF-beta in the intact organism. We will review the pertinent features of some of these models, and discuss new insights provided by these studies into regulation and role of TGF-beta in health and disease.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0378-0392
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
24
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
154-60
|
pubmed:dateRevised |
2005-11-16
|
pubmed:meshHeading |
pubmed-meshheading:9525699-Animals,
pubmed-meshheading:9525699-Disease,
pubmed-meshheading:9525699-Gene Expression,
pubmed-meshheading:9525699-Humans,
pubmed-meshheading:9525699-Mice,
pubmed-meshheading:9525699-Mice, Transgenic,
pubmed-meshheading:9525699-Mutagenesis,
pubmed-meshheading:9525699-Receptors, Transforming Growth Factor beta,
pubmed-meshheading:9525699-Signal Transduction,
pubmed-meshheading:9525699-Transforming Growth Factor beta
|
pubmed:year |
1998
|
pubmed:articleTitle |
Lessons from TGF-beta transgenic mice.
|
pubmed:affiliation |
Division of Nephrology, Albert Einstein College of Medicine, Bronx, NY 10461-1602, USA. bottinge@aecom.yu.edu
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pubmed:publicationType |
Journal Article,
Review
|