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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
1998-5-13
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pubmed:abstractText |
Expression cloning revealed a chloride channel (ICln) that we found to be fundamental for the regulatory volume decrease in a variety of cells. The chromosomal localization of the human ICln-gene showed two loci, one at chromosome 11 in position q13.5-q14.1, termed CLNS1A, and a second one at chromosome 6 at position p12.1-q13, termed CLNS1B. In this study, we offer a detailed characterization of the CLNS1A gene and provide the exact position (6p12) and sequence data of CLNS1B, an intronless gene 91.3% homologous to the coding region of CLNS1A.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0378-1119
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pubmed:author |
pubmed-author:BergmannFF,
pubmed-author:DeetjenPP,
pubmed-author:ErdelMM,
pubmed-author:FürstJJ,
pubmed-author:GaliettaL JLJ,
pubmed-author:GschwentnerMM,
pubmed-author:HoffaEE,
pubmed-author:ModyD GDG,
pubmed-author:MusanteLL,
pubmed-author:OehmCC,
pubmed-author:PaulmichlMM,
pubmed-author:ScandellaEE,
pubmed-author:SchmardaAA,
pubmed-author:UtermannGG
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pubmed:issnType |
Print
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pubmed:day |
16
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pubmed:volume |
209
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
59-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9524223-Amino Acid Sequence,
pubmed-meshheading:9524223-Base Sequence,
pubmed-meshheading:9524223-Chloride Channels,
pubmed-meshheading:9524223-Chromosome Mapping,
pubmed-meshheading:9524223-Chromosomes, Human, Pair 11,
pubmed-meshheading:9524223-Chromosomes, Human, Pair 6,
pubmed-meshheading:9524223-DNA Primers,
pubmed-meshheading:9524223-Exons,
pubmed-meshheading:9524223-Genomic Library,
pubmed-meshheading:9524223-Humans,
pubmed-meshheading:9524223-In Situ Hybridization, Fluorescence,
pubmed-meshheading:9524223-Introns,
pubmed-meshheading:9524223-Ion Channels,
pubmed-meshheading:9524223-Molecular Sequence Data,
pubmed-meshheading:9524223-Open Reading Frames,
pubmed-meshheading:9524223-Polymerase Chain Reaction,
pubmed-meshheading:9524223-Sequence Alignment,
pubmed-meshheading:9524223-Sequence Homology, Amino Acid,
pubmed-meshheading:9524223-Sequence Homology, Nucleic Acid
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pubmed:year |
1998
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pubmed:articleTitle |
Characterization of the human gene coding for the swelling-dependent chloride channel ICln at position 11q13.5-14.1 (CLNS1A) and further characterization of the chromosome 6 (CLNS1B) localization.
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pubmed:affiliation |
Department of Physiology, University of Innsbruck, Fritz-Pregl-Strasse 3, A-6020, Innsbruck, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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