rdf:type |
|
lifeskim:mentions |
umls-concept:C0003234,
umls-concept:C0012860,
umls-concept:C0017262,
umls-concept:C0020789,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0085983,
umls-concept:C0086661,
umls-concept:C0185117,
umls-concept:C0205263,
umls-concept:C0243071,
umls-concept:C0301625,
umls-concept:C0598312,
umls-concept:C1458155,
umls-concept:C2911684
|
pubmed:issue |
5
|
pubmed:dateCreated |
1998-4-6
|
pubmed:abstractText |
Studies were designed to elucidate the basis for the antiproliferative activity of the anthracycline antibiotic, idarubicin (4-demethoxy-daunorubicin) in MCF-7 breast tumor cells.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0344-5704
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
41
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
361-9
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:9523731-Antibiotics, Antineoplastic,
pubmed-meshheading:9523731-Apoptosis,
pubmed-meshheading:9523731-Breast Neoplasms,
pubmed-meshheading:9523731-Cell Division,
pubmed-meshheading:9523731-DNA, Neoplasm,
pubmed-meshheading:9523731-DNA Damage,
pubmed-meshheading:9523731-Dose-Response Relationship, Drug,
pubmed-meshheading:9523731-Female,
pubmed-meshheading:9523731-Genes, myc,
pubmed-meshheading:9523731-Humans,
pubmed-meshheading:9523731-Idarubicin,
pubmed-meshheading:9523731-Tumor Cells, Cultured
|
pubmed:year |
1998
|
pubmed:articleTitle |
Induction of DNA damage, inhibition of DNA synthesis and suppression of c-myc expression by the anthracycline analog, idarubicin (4-demethoxy-daunorubicin) in the MCF-7 breast tumor cell line.
|
pubmed:affiliation |
Department of Medicine, Medical College of Virginia, Richmond 23298, USA. GEWIRTZ@Gems.VCU.EDU
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|