Linked Life Data

9522966

Source:http://linkedlifedata.com/resource/pubmed/id/9522966

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-5-6
pubmed:abstractText
Understanding the biological function of the fat retained during pregnancy is important when estimating energy needs during reproduction. Women as well as rats are often considered to gain fat at specific anatomical sites during pregnancy and use this fat as a source of energy during lactation. However, mobilized body fat covers only a minor part of the energy needed by the lactating rat dam. In this paper, fat cell size, lipoprotein lipase activity, as well as triglyceride turnover in parametrial and subcutaneous adipose tissues were studied during the first 2 weeks of gestation and in virginal controls to further explore the metabolic and physiological basis for changes in body fat during reproduction in rats. Pregnancy increased the size of parametrial but not of subcutaneous adipocytes. The lipoprotein lipase activity in subcutaneous adipocytes was not increased by pregnancy. The accumulation in adipose tissue of 14C from orally administered 14C-oleic acid was higher in virginal than in pregnant rats. No effect of pregnancy on the rate of lipid turnover in parametrial or subcutaneous adipocytes was found. The findings are in accordance with the contention that body fat gained during rat pregnancy, to a large extent, is a consequence of a general growth of maternal tissues rather than the result of a stimulating effect of pregnancy on fat accumulation by adipocytes from specific body sites.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0250-6807
pubmed:author
pubmed:issnType
Print
pubmed:volume
42
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Triglyceride turnover, lipoprotein lipase activity, and fat cell size in adipose tissue of rats during the first 2 weeks of pregnancy.
pubmed:affiliation
Department of Physiology and Pharmacology, Karolinska Institute, Stockholm.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't