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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
4
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|
pubmed:dateCreated |
1998-4-30
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|
pubmed:abstractText |
Concentrations of quinolinic acid, an N-methyl-D-aspartate agonist, are often elevated for long periods of time in the cerebrospinal fluid (CSF) and brain tissue of patients with AIDS dementia complex (ADC). This study was designed to test the hypothesis that chronic exposure of human neurons to quinolinic acid levels equivalent to those in the CSF of ADC patients is neurotoxic.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
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pubmed:issn |
0269-9370
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
5
|
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pubmed:volume |
12
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
355-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9520164-AIDS Dementia Complex,
pubmed-meshheading:9520164-Cells, Cultured,
pubmed-meshheading:9520164-Dose-Response Relationship, Drug,
pubmed-meshheading:9520164-Humans,
pubmed-meshheading:9520164-Image Processing, Computer-Assisted,
pubmed-meshheading:9520164-Immunohistochemistry,
pubmed-meshheading:9520164-Microscopy, Electron, Scanning,
pubmed-meshheading:9520164-Microscopy, Electron, Scanning Transmission,
pubmed-meshheading:9520164-Neurons,
pubmed-meshheading:9520164-Quinolinic Acid,
pubmed-meshheading:9520164-Receptors, N-Methyl-D-Aspartate,
pubmed-meshheading:9520164-Time Factors
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|
pubmed:year |
1998
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|
pubmed:articleTitle |
Chronic exposure of human neurons to quinolinic acid results in neuronal changes consistent with AIDS dementia complex.
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pubmed:affiliation |
Centre for Immunology, St Vincent's Hospital, Sydney, Australia.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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