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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1998-4-20
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pubmed:abstractText |
The effects of preparations of Chinese medicinal prescriptions on the activities of digestive enzymes were investigated. The starch dextrinizing activity of pancreatin was inhibited by Keishi-bukuryo-gan, Sho-seiryu-to, Hachimi-jio-gan, Unsei-in and Keishi-ka-shakuyaku-to to below 40% of the control activity. Hachimi-jio-gan and Sho-seiryu-to, in particular, lowered the activity to 4% and 24% of the control activity, respectively. The protein digestive activity of pancreatin was lowered by Keishi-bukuryo-gan, Oren-gedoku-to, Ryutan-shakan-to, Tokaku-joki-to, Yokuinin-to and Hange-shashin-to, to 56 to 70% of the control activity. To investigate the effects of the preparations of Chinese medicinal prescriptions on digestive enzymes in vivo, 600 mg (185 kBq) of 125I-egg white albumin were administered orally to rats 30 min before the administration of 100 mg of Tokaku-joki-to or Oren-gedoku-to. The radioactivity which transferred to the blood was less in the animals pre-fed these prescriptions than in the control animals, indicating that the digestion of egg white albumin was delayed in the presence of the prescriptions.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Albumins,
http://linkedlifedata.com/resource/pubmed/chemical/Amylases,
http://linkedlifedata.com/resource/pubmed/chemical/Drugs, Chinese Herbal,
http://linkedlifedata.com/resource/pubmed/chemical/Iodine Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Pancreatin,
http://linkedlifedata.com/resource/pubmed/chemical/Pepsin A
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0918-6158
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
133-9
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9514607-Albumins,
pubmed-meshheading:9514607-Amylases,
pubmed-meshheading:9514607-Animals,
pubmed-meshheading:9514607-Digestive System,
pubmed-meshheading:9514607-Drugs, Chinese Herbal,
pubmed-meshheading:9514607-Humans,
pubmed-meshheading:9514607-Iodine Radioisotopes,
pubmed-meshheading:9514607-Kinetics,
pubmed-meshheading:9514607-Male,
pubmed-meshheading:9514607-Pancreatin,
pubmed-meshheading:9514607-Pepsin A,
pubmed-meshheading:9514607-Rats,
pubmed-meshheading:9514607-Rats, Wistar
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pubmed:year |
1998
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pubmed:articleTitle |
Effects of preparations of Chinese medicinal prescriptions on digestive enzymes in vitro and in vivo.
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pubmed:affiliation |
Osaka Prefectural Institute of Public Health, Japan.
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pubmed:publicationType |
Journal Article
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