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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1998-4-7
|
| pubmed:abstractText |
We compared cardiac troponins T (cTnT) and I (cTnI) collected within 3.5 h of ischemic symptoms for predicting clinical outcomes in 770 patients. cTnT (cutoff > 0.1 microgram/L) and cTnI (cutoff > 1.5 micrograms/L) were concordant (both positive or negative) in 90.4% of patients. Among discordant results, 66 were cTnT positive and cTnI negative vs 8 who showed the reverse (P < 0.001). Five cTnT-positive and cTnI-negative patients died within 30 days; none who were cTnT negative and cTnI positive died. cTnT showed a slightly greater association (chi 2 = 18.0, P < 0.001) with 30-day mortality than cTnI (chi 2 = 12.5, P = 0.002). The area of the ROC curve for predicting 30-day mortality was significantly larger (Z = 2.08; P = 0.0375) for cTnT, at 0.68 [95% confidence interval (CI) 0.60-0.75], compared with cTnI, at 0.64 (95% CI 0.56-0.72). When cTnI and the electrocardiogram (ECG) were put in a logistic multiple regression model, cTnT added significant information (chi 2 = 8.03, P = 0.045); however, cTnI did not add to a model containing cTnT and the ECG (chi 2 = 0.84, P = 0.657). cTnT provided more information than cTnI for predicting 30-day mortality early after presentation with acute coronary syndromes.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Mar
|
| pubmed:issn |
0009-9147
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
44
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
494-501
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9510853-Aged,
pubmed-meshheading:9510853-Biological Markers,
pubmed-meshheading:9510853-Chest Pain,
pubmed-meshheading:9510853-Coronary Disease,
pubmed-meshheading:9510853-Electrocardiography,
pubmed-meshheading:9510853-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:9510853-Female,
pubmed-meshheading:9510853-Fluorescent Antibody Technique,
pubmed-meshheading:9510853-Humans,
pubmed-meshheading:9510853-Male,
pubmed-meshheading:9510853-Middle Aged,
pubmed-meshheading:9510853-Myocardial Infarction,
pubmed-meshheading:9510853-Regression Analysis,
pubmed-meshheading:9510853-Reproducibility of Results,
pubmed-meshheading:9510853-Risk Assessment,
pubmed-meshheading:9510853-Sensitivity and Specificity,
pubmed-meshheading:9510853-Treatment Outcome,
pubmed-meshheading:9510853-Troponin,
pubmed-meshheading:9510853-Troponin I,
pubmed-meshheading:9510853-Troponin T
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Cardiac troponin T and cardiac troponin I: relative values in short-term risk stratification of patients with acute coronary syndromes. GUSTO-IIa Investigators.
|
| pubmed:affiliation |
Department of Pathology, University of Maryland School of Medicine, Baltimore, USA. rchriste@umms001.ab.umd.edu
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study
|