Linked Life Data

9509904

Source:http://linkedlifedata.com/resource/pubmed/id/9509904

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-4-2
pubmed:abstractText
The etiology of Behçet's disease has been proposed as being a viral, bacterial, genetic and immunological disorder. After Hulusi Behçet's viral etiological hypothesis, many investigators have tried to confirm this. Scrapings and fluids from patients were applied to subculture in chorioallantoic membranes of fertilized eggs as well as in mice and rabbits by direct intracerebral injection. Since the 1980s, in situ hybridization, blotting, and polymerase chain reaction has also been applied to identify the herpes simplex virus DNA and RNA in patients. Animal models were developed based on environmental pollutants, bacterial and human heat shock protein derived peptides and virus injection. Using these animal models separately and/or concurrently, allows for a more effective investigation into Behçet's disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0513-5796
pubmed:author
pubmed:issnType
Print
pubmed:volume
38
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-64
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Etiopathology of Behçet's disease: herpes simplex virus infection and animal model.
pubmed:affiliation
Laboratory of Cell Biology, Ajou University Institute for Medical Sciences, Suwon, Korea. sohnsh@madang.ajou.ac.kr
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't