Linked Life Data

95087

Source:http://linkedlifedata.com/resource/pubmed/id/95087

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1980-9-28
pubmed:abstractText
The phosphorylcholine antigens (C substance) were specifically isolated from Nippostrongglus brasiliensis adult worms. They formed a gorup of fairly closely related molecules, but it was not possible to evidence that the carrier molecule was unique. An indirect immunoenzymatic test using immobilized lectins (concanavalin A, phytohaemagglutinin Els, wheat germ agglutinin, recin types I and II, peanut agglutinin) gave some light on the carbohydrate composition of the carrier molecules, whereas the amino acid part of these molecules seemed to indicate an unique oligopeptide, the composition of which would be: Asx (4), Thr (2), Ser (4), Glux (6), Gly (6) Ala (3), Val (2), Ile (1), Leu (2), Phe (8), Lys (2), Arg (1). An epitope of the carrier molecules was demonstrated with anti-N. brasiliensis egg antisera. It was shared with various pathogens including Haemonchus contortus, Schistosoma mansoni and Dipetalonema vitae. It was also found on the purified pneumococcal C. polysaccharide. The C. substance from a variety of parasites can now be isolated by a combination of specific reactions using both anti-phosphorylcholine and anti-carrier molecule antibodies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-4910
pubmed:author
pubmed:issnType
Print
pubmed:volume
130
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
889-900
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:articleTitle
Phosphorylcholine antigens from Nippostrongylus brasiliensis. II.--Isolation and partial characterization of phosphorylcholine antigens from adult worm.
pubmed:publicationType
Journal Article