Linked Life Data

9503368

Source:http://linkedlifedata.com/resource/pubmed/id/9503368

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1998-4-8
pubmed:abstractText
Type XII collagen belongs to the sub-family of fibril associated collagens with interrupted triple helices (FACITs). It has been shown to be present in bovine fetal epiphyseal cartilage but is absent in hyaline cartilage in avian and murine species. Here, we report the detection of type XII collagen transcripts by RT-PCR and Northern blot analysis in human fetal epiphyseal chondrocytes. Northern blot analysis demonstrated that cultured dermal fibroblasts and fetal epiphyseal chondrocytes contained predominantly transcripts for the large form of type XII collagen (XIIA). Dot blot analysis of RNA from human cells indicated that type XII collagen was two-fold more abundant in dermal fibroblasts compared to fetal chondrocytes. Northern blot analysis of multiple human tissues indicated that type XII collagen was expressed in heart, placenta, lung, skeletal muscle and pancreas.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0945-053X
pubmed:author
pubmed:issnType
Print
pubmed:volume
16
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
343-8
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
Characterization of human chondrocyte and fibroblast type XII collagen cDNAs.
pubmed:affiliation
Department of Medicine, Jefferson Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.