Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1998-4-30
pubmed:abstractText
The purpose of the study was to test a newly developed, MR-compatible, liquid nitrogen-cooled cryoprobe. The probe has an outer diameter of 3.5 mm and was specifically developed for percutaneous, MR-guided, interstitial cryotherapy. The probe was inserted percutaneously into the livers of 10 rabbits. The cryotherapy procedure was monitored with a surface coil in a 1.5 Tesla magnet using a gradient echo sequence. Follow-up examinations were performed 3 and 7 days after the freezing procedure using T1- and T2-weighted spin echo sequences. At 7 days the animals were sacrificed and the cryolesions were examined histologically. The cryoprobe enabled artifact-free MR imaging of the "iceball" formation during freezing of the rabbit liver. After 1 min of freezing, the iceball at the tip of the probe showed an average maximum diameter of 10.8 mm. No bleeding complications were observed during or after the freezing procedure. Histologic examination 7 days after cryotherapy confirmed that the liver lesions were the same size as had been predicted by the images of the acute iceball. This new, percutaneously inserted, MR-compatible, liquid-nitrogen cooled cryoprobe allows accurate, artifact-free MR imaging of interstitial cryotherapy.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0740-3194
pubmed:author
pubmed:issnType
Print
pubmed:volume
39
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
354-60
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:9498590-Animals, pubmed-meshheading:9498590-Artifacts, pubmed-meshheading:9498590-Bile Ducts, Intrahepatic, pubmed-meshheading:9498590-Blood Loss, Surgical, pubmed-meshheading:9498590-Blood Vessels, pubmed-meshheading:9498590-Boron Compounds, pubmed-meshheading:9498590-Contrast Media, pubmed-meshheading:9498590-Cryosurgery, pubmed-meshheading:9498590-Disease Models, Animal, pubmed-meshheading:9498590-Equipment Design, pubmed-meshheading:9498590-Female, pubmed-meshheading:9498590-Follow-Up Studies, pubmed-meshheading:9498590-Forecasting, pubmed-meshheading:9498590-Glass, pubmed-meshheading:9498590-Granulation Tissue, pubmed-meshheading:9498590-Liver, pubmed-meshheading:9498590-Magnetic Resonance Imaging, pubmed-meshheading:9498590-Monitoring, Intraoperative, pubmed-meshheading:9498590-Necrosis, pubmed-meshheading:9498590-Nitrogen, pubmed-meshheading:9498590-Postoperative Hemorrhage, pubmed-meshheading:9498590-Rabbits, pubmed-meshheading:9498590-Radiology, Interventional, pubmed-meshheading:9498590-Silicates, pubmed-meshheading:9498590-Surface Properties, pubmed-meshheading:9498590-Thrombosis
pubmed:year
1998
pubmed:articleTitle
MR-guided interstitial cryotherapy of the liver with a novel, nitrogen-cooled cryoprobe.
pubmed:affiliation
Department of Diagnostic Radiology, University of Technology, Aachen, Germany.
pubmed:publicationType
Journal Article