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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1998-3-24
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pubmed:abstractText |
Genetic diversity of 32 Helicobacter pylori strains isolated from patients with gastritis, gastric or duodenal ulcer, carcinoma, or lymphoma was determined by repetitive sequence element polymerase chain reaction (REP-PCR), and by the new typing method restriction fragment end-labelling (RFEL). Furthermore, these two methods were used to investigate a possible correlation between clinical symptoms and the genetic background of Helicobacter pylori. Both REP-PCR and RFEL revealed 31 different patterns for the 32 strains tested, but the pair of isolates with identical REP-PCR patterns was not the same as the pair of isolates with identical RFEL patterns. Computer-assisted analysis of the DNA fingerprints was used to determine similarity coefficients. This analysis revealed no clustering of disease-specific strains by any of the two methods.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0378-1097
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
160
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
145-50
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9495025-DNA, Bacterial,
pubmed-meshheading:9495025-DNA Fingerprinting,
pubmed-meshheading:9495025-DNA Primers,
pubmed-meshheading:9495025-Gastritis,
pubmed-meshheading:9495025-Genome, Bacterial,
pubmed-meshheading:9495025-Genotype,
pubmed-meshheading:9495025-Helicobacter pylori,
pubmed-meshheading:9495025-Humans,
pubmed-meshheading:9495025-Polymerase Chain Reaction,
pubmed-meshheading:9495025-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:9495025-Sequence Analysis, DNA
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pubmed:year |
1998
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pubmed:articleTitle |
Genomic DNA fingerprinting of clinical isolates of Helicobacter pylori by REP-PCR and restriction fragment end-labelling.
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pubmed:affiliation |
Department of Medical Microbiology, Vrije Universiteit Amsterdam, The Netherlands. NEM.van_Doorn.MM@med.vu.nl
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pubmed:publicationType |
Journal Article
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