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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
1998-3-10
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pubmed:abstractText |
Previous studies have shown that thrombin is a potent though slow-acting mitogen for vascular smooth muscle cells (SMC). Because thrombin generation in vivo is accompanied by platelet activation, it has been suggested that platelet-derived factors might enhance thrombin-induced SMC proliferation. No information is available so far on the possible role of thromboxane A2.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0009-7322
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
17
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pubmed:volume |
97
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
589-95
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9494030-15-Hydroxy-11 alpha,9...,
pubmed-meshheading:9494030-Animals,
pubmed-meshheading:9494030-Calcium-Calmodulin-Dependent Protein Kinases,
pubmed-meshheading:9494030-Cattle,
pubmed-meshheading:9494030-Cells, Cultured,
pubmed-meshheading:9494030-Coronary Vessels,
pubmed-meshheading:9494030-DNA,
pubmed-meshheading:9494030-Drug Synergism,
pubmed-meshheading:9494030-Female,
pubmed-meshheading:9494030-Mitosis,
pubmed-meshheading:9494030-Muscle, Smooth, Vascular,
pubmed-meshheading:9494030-RNA, Messenger,
pubmed-meshheading:9494030-Receptors, Thromboxane,
pubmed-meshheading:9494030-Thrombin,
pubmed-meshheading:9494030-Thromboxane A2,
pubmed-meshheading:9494030-Up-Regulation
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pubmed:year |
1998
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pubmed:articleTitle |
Thrombin-induced mitogenesis in coronary artery smooth muscle cells is potentiated by thromboxane A2 and involves upregulation of thromboxane receptor mRNA.
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pubmed:affiliation |
Institut für Klinische Anaesthesiologie, Heinrich-Heine-Universität Düsseldorf, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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