Linked Life Data

9492620

Source:http://linkedlifedata.com/resource/pubmed/id/9492620

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1998-4-23
pubmed:abstractText
After 15 years of intense AIDS research several fascinating new findings have recently produced real hope for people infected with HIV and new optimism among scientists. A second group of powerful antiretroviral drugs (proteinase inhibitors) has been introduced. These drugs can virtually stop viral replication when used in combination with other drugs (nucleoside or non-nucleoside reverse transcriptase inhibitors), which also almost totally eliminates the emergence of HIV-resistance. New moleculargenetic methods (plasma HIV-RNA assays) made a new marker to quantify and survey therapeutic effects and to accurately predict individual progression of HIV infection available. These new instruments also provided us with a more realistic imagination about pathogenesis and viral dynamics in HIV infection. In neonates prophylactic antiretroviral treatment of pregnant women already prevents two thirds of vertically acquired infections, and the vertical transmission rate may well continue to decline with new prophylactic regimens and/or other interventions (e.g. cesarean section). Given these splendid innovations, a huge impact on prognosis can well be anticipated in the near future.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0040-5930
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
57-64
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
1998
pubmed:articleTitle
[HIV infection: relevant pediatric aspects].
pubmed:affiliation
Pädiatrische Universitätsklinik, Basler Kinderspital.
pubmed:publicationType
Journal Article, English Abstract, Review