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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
1976-10-1
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pubmed:abstractText |
In the present experiment, study was made of the effects of melengestrol acetate given to heifers (0.5 mg for 14 days, starting at day 15 of the estrous cycle) on carbohydrate histochemical and histologic features of the ampulla of the uterine tube (oviduct). Melengestrol acetate-treated animals had significantly (P less than 0.5) fewer fertilized ova at 3 days after mating (50%) as compared with control animals (100%). Estrussynchronization treatment with melengestrol acetate reduced the amount of cytoplasmic and nuclear extrusions from the secretory cells of the uterine tubular ampulla, but did not alter the amount or types of mucosubstances within these cells.
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pubmed:keyword |
http://linkedlifedata.com/resource/pubmed/keyword/Animals, Laboratory,
http://linkedlifedata.com/resource/pubmed/keyword/Biology,
http://linkedlifedata.com/resource/pubmed/keyword/Carbohydrate Metabolic Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research,
http://linkedlifedata.com/resource/pubmed/keyword/Comparative Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Contraception,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents...,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents, Female--side...,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents...,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents...,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive...,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Agents--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Methods--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Contraceptive Mode Of Action,
http://linkedlifedata.com/resource/pubmed/keyword/Cytologic Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Estrogens,
http://linkedlifedata.com/resource/pubmed/keyword/Fallopian Tubes,
http://linkedlifedata.com/resource/pubmed/keyword/Family Planning,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia,
http://linkedlifedata.com/resource/pubmed/keyword/Genitalia, Female,
http://linkedlifedata.com/resource/pubmed/keyword/Histochemical Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Hormone Receptors,
http://linkedlifedata.com/resource/pubmed/keyword/Inhibition Of Fertilization,
http://linkedlifedata.com/resource/pubmed/keyword/Metabolic Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Oral Contraceptives--side effects,
http://linkedlifedata.com/resource/pubmed/keyword/Ovulation,
http://linkedlifedata.com/resource/pubmed/keyword/Physiology,
http://linkedlifedata.com/resource/pubmed/keyword/Reproduction,
http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology,
http://linkedlifedata.com/resource/pubmed/keyword/Studies,
http://linkedlifedata.com/resource/pubmed/keyword/Tubal Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Urogenital System,
http://linkedlifedata.com/resource/pubmed/keyword/Uterine Effects,
http://linkedlifedata.com/resource/pubmed/keyword/Uterus
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0002-9645
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
37
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
901-3
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pubmed:dateRevised |
2005-11-17
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pubmed:otherAbstract |
PIP: Only heifers with estrous cycles of 18-22 days were used; 20 were in the experimental group and 20 were controls. Melengestrol acetate, .5 mg/animal/day for 14 days, was added to the grain ration, starting on Day 15 of an estrous cycle. Following drug withdrawal, each heifer was mated with 2 bulls at the synchronized estrus and killed 3 days later. Control heifers were killed after mating. The uterine tubes were flushed with saline solution to remove ova. An ovum was considered fertilized if cleavage had occurred and sperm were in the zona pellucida. Tubal tissues were prepared and studied with different stains. All heifers had ovulated. Melengestrol-acetate-treated heifers had signficantly (p less than .5) fewer fertilized ova 3 days after mating. Estrous synchronization treatment with melengestrol acetate reduced the amount of cytoplasmic and nuclear extrusions from the secretory cells of the tubular ampulla but did not alter the amount or types of mucosubstances within these cells. The major steroidogenic effect was considered to be estrogenic. However, the histologic and histochemical alterations observed were not estrogenic. Estrogen-dependent physiologic responses in reproductive tissues may be related to the number of estrogen-binding sites.
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pubmed:meshHeading |
pubmed-meshheading:949117-Animals,
pubmed-meshheading:949117-Carbohydrate Metabolism,
pubmed-meshheading:949117-Cattle,
pubmed-meshheading:949117-Cytoplasmic Granules,
pubmed-meshheading:949117-Epithelial Cells,
pubmed-meshheading:949117-Epithelium,
pubmed-meshheading:949117-Fallopian Tubes,
pubmed-meshheading:949117-Female,
pubmed-meshheading:949117-Fertilization,
pubmed-meshheading:949117-Histocytochemistry,
pubmed-meshheading:949117-Melengestrol Acetate,
pubmed-meshheading:949117-Pregnadienes
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pubmed:year |
1976
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pubmed:articleTitle |
Influence of a progestogen on carbohydrate histochemical and histologic features of the ampulla of the bovine uterine tube.
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pubmed:publicationType |
Journal Article
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