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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1998-3-19
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pubmed:abstractText |
MHC class I associated peptides on cancer cells represent potential targets for CD8+ cytotoxic T cell activity against tumor cells. We eluted the naturally bound MHC class I peptides of a colon carcinoma cell line and compared them to peptides isolated from a B cell line and a slow-growing activated Ki-ras-disrupted colon cancer cell line. While we failed to detect any significant differences in class I associated peptides due to the presence or absence of activated Ki-ras in colon cancer cell lines, the colon cancer cell lines and B cell line presented vastly different peptide repertoires in the context of HLA-A*0201 molecules.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0304-3835
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
30
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
193-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9489488-Antigens, CD8,
pubmed-meshheading:9489488-B-Lymphocytes,
pubmed-meshheading:9489488-Cell Line, Transformed,
pubmed-meshheading:9489488-Colonic Neoplasms,
pubmed-meshheading:9489488-Genes, MHC Class I,
pubmed-meshheading:9489488-Genes, ras,
pubmed-meshheading:9489488-HLA-A Antigens,
pubmed-meshheading:9489488-Herpesvirus 4, Human,
pubmed-meshheading:9489488-Humans,
pubmed-meshheading:9489488-Mutagenesis, Insertional,
pubmed-meshheading:9489488-Tumor Cells, Cultured
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pubmed:year |
1998
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pubmed:articleTitle |
MHC class I bound peptides of a colon carcinoma cell line, a Ki-ras gene-targeted progeny cell line and a B cell line.
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pubmed:affiliation |
Department of Genetics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|