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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1998-3-19
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pubmed:abstractText |
Minimizing secondary injury after severe traumatic brain injury (TBI) is the primary goal of cerebral resuscitation. For more than two decades, hyperventilation has been one of the most often used strategies in the management of TBI. Laboratory and clinical studies, however, have verified a post-TBI state of reduced cerebral perfusion that may increase the brain's vulnerability to secondary injury. In addition, it has been suggested in a clinical study that hyperventilation may worsen outcome after TBI.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-3085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
88
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
549-56
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9488311-Anesthetics, Inhalation,
pubmed-meshheading:9488311-Animals,
pubmed-meshheading:9488311-Blood Glucose,
pubmed-meshheading:9488311-Blood Pressure,
pubmed-meshheading:9488311-Body Temperature,
pubmed-meshheading:9488311-Brain Concussion,
pubmed-meshheading:9488311-Carbon Dioxide,
pubmed-meshheading:9488311-Cell Death,
pubmed-meshheading:9488311-Cell Survival,
pubmed-meshheading:9488311-Cerebrovascular Circulation,
pubmed-meshheading:9488311-Disease Models, Animal,
pubmed-meshheading:9488311-Follow-Up Studies,
pubmed-meshheading:9488311-Hippocampus,
pubmed-meshheading:9488311-Intubation, Intratracheal,
pubmed-meshheading:9488311-Isoflurane,
pubmed-meshheading:9488311-Male,
pubmed-meshheading:9488311-Neurons,
pubmed-meshheading:9488311-Postural Balance,
pubmed-meshheading:9488311-Psychomotor Performance,
pubmed-meshheading:9488311-Random Allocation,
pubmed-meshheading:9488311-Rats,
pubmed-meshheading:9488311-Rats, Sprague-Dawley,
pubmed-meshheading:9488311-Respiration, Artificial,
pubmed-meshheading:9488311-Resuscitation,
pubmed-meshheading:9488311-Single-Blind Method,
pubmed-meshheading:9488311-Treatment Outcome
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pubmed:year |
1998
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pubmed:articleTitle |
Augmented neuronal death in CA3 hippocampus following hyperventilation early after controlled cortical impact.
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pubmed:affiliation |
Safar Center for Resuscitation Research, The University of Pittsburgh Brain Trauma Research Center, and Department of Anesthesiology/Critical Care Medicine, Pennsylvania 15260, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
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