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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2 Pt 2
|
| pubmed:dateCreated |
1998-3-17
|
| pubmed:abstractText |
Arterial pressure (AP), heart rate (HR), cardiac sympathetic tonus (ST), and parasympathetic tonus (PT) were determined in spontaneously hypertensive rats (SHR, 8 male and 8 female) and Wistar-Kyoto normotensive rats (WKY, 8 male and 12 female) before and after acute exercise. Before exercise, hypertensive rats (regardless of gender) had an increased ST (+15 beats/min), increased resting HR (+12 beats/min), and decreased PT (-11 beats/min). Similarly, female rats (regardless of strain) also had an increased ST (+15 beats/min), increased resting HR (+39 beats/min), and decreased PT (-14 beats/min). Hypertensive rats had a significant reduction in AP (-17 +/- 3 mmHg), ST (-26 beats/min), PT (-7 beats/min), and HR (-14 beats/min) after exercise. In contrast, AP was not reduced in normotensive rats and ST (+18 beats/min) and HR (+42 beats/min) were increased in female normotensive rats after exercise. However, male normotensive rats had a postexercise reduction in ST (-14 beats/min) and HR (-19 beats/min). In summary, AP, ST, and resting HR were higher whereas PT was lower in hypertensive vs. normotensive rats. Furthermore, females had a higher resting HR, intrinsic HR, and ST and lower PT than male rats. These data demonstrate that gender and the resting level of AP influence cardiac autonomic regulation.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Feb
|
| pubmed:issn |
0002-9513
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
274
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
R510-6
|
| pubmed:dateRevised |
2008-11-21
|
| pubmed:meshHeading |
pubmed-meshheading:9486311-Adrenergic alpha-Antagonists,
pubmed-meshheading:9486311-Animals,
pubmed-meshheading:9486311-Autonomic Nervous System,
pubmed-meshheading:9486311-Blood Pressure,
pubmed-meshheading:9486311-Female,
pubmed-meshheading:9486311-Heart,
pubmed-meshheading:9486311-Heart Rate,
pubmed-meshheading:9486311-Hypertension,
pubmed-meshheading:9486311-Male,
pubmed-meshheading:9486311-Metoprolol,
pubmed-meshheading:9486311-N-Methylscopolamine,
pubmed-meshheading:9486311-Parasympathetic Nervous System,
pubmed-meshheading:9486311-Parasympatholytics,
pubmed-meshheading:9486311-Physical Exertion,
pubmed-meshheading:9486311-Rats,
pubmed-meshheading:9486311-Rats, Inbred SHR,
pubmed-meshheading:9486311-Rats, Inbred WKY,
pubmed-meshheading:9486311-Sex Characteristics,
pubmed-meshheading:9486311-Sympathetic Nervous System
|
| pubmed:year |
1998
|
| pubmed:articleTitle |
Acute exercise and gender alter cardiac autonomic tonus differently in hypertensive and normotensive rats.
|
| pubmed:affiliation |
Department of Physiology, College of Medicine, Northeastern Ohio Universities, Rootstown 44272, USA.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|