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pubmed-article:9485094pubmed:abstractTextWe have previously shown that the woven pagetic bone in patients with Paget's disease is characterized by an impaired degree of beta-isomerization of C-telopeptides of type I collagen molecules, which results in a preferential urinary excretion of nonisomerized type I collagen C-telopeptide breakdown products (CTX). The aim of this study was to measure the urinary excretion of nonisomerized (alpha) and beta-isomerized (beta) CTX in patients with Paget's disease treated with a bisphosphonate.lld:pubmed
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pubmed-article:9485094pubmed:articleTitleMeasurement of urinary excretion of nonisomerized and beta-isomerized forms of type I collagen breakdown products to monitor the effects of the bisphosphonate zoledronate in Paget's disease.lld:pubmed
pubmed-article:9485094pubmed:affiliationINSERM, Lyon, France.lld:pubmed
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